Characterization of focal liver lesions using ferucarbotran-enhanced liver MRI: efficacy of percentage signal intensity loss for detecting nodules within diffuse liver disease
نویسندگان
چکیده
Introduction: Early detection of HCC is important in improving patient outcome and decision making in therapeutic strategies. Many authors reported superparamagnetic iron oxide (SPIO) enhanced magnetic resonance imaging (MRI) is effective for the differentiation of benign and malignant hepatic lesions and the percentage of signal intensity loss (PSIL) might reflect Kupffer-cell numbers in tumors. A newly developed SPIO, ferucarbotran is primarily taken up by the Kupffer cells of the liver. The purpose of our study was to determine the optimal threshold value of PSIL for the characterization of focal liver lesions among patients with diffuse liver disease.
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